Retford O. Berko, PhD, Esq. Of Counsel
FDA Lawyer and Registered Patent Attorney
Tel +1 (301) 982 0152
Email: Retford@dobelawgroup.com
Retford is an FDA Lawyer and a Registered Patent Attorney. His practice is focused on all phases of FDA law and practice and in patent prosecution and drafting in the areas of chemical and biochemical sciences. Retford completed his Ph.D. in Biochemistry at University of North Carolina at Chapel Hill, with emphasis in enzyme kinetics and mechanism. He then embarked on postdoctoral research in areas of steroid chemistry, clinical chemistry, tumor immunology and cancer prevention and control at University of Illinois at Chicago and National Cancer Institute in Bethesda, Maryland. Retford spent twelve years at the FDA as Review Chemist and Compliance Officer where he worked on medical device, biologic and combination product regulation. After completing law school, Retford spent approximately three years at the USPTO as Patent Examiner where his focus was in the prosecution of chemical and drug compositions, biochemical assays and drug delivery medical devices systems.
Practice Areas and Interests
- All phases of FDA law including drug, medical device, biologics and combination products regulations including dossier review, filing and opinion papers.
- Patent prosecution and drafting
Education
- J.D. University of Missouri-Kansas City School of Law (2002)
- Ph.D. University of North Carolina at Chapel Hill (1979)
Bar Admissions
- District of Columbia
- United States Patent &Trademark Office
Professional Affiliations
- Patent Law Community of Greater Washington (PLCW)
Publications
- Berko, R., Light, L., Krebs-Smith, J. and Weed, D.: Novel Cancer Prevention and Control Strategies in Special Populations. Abstract M 26, National Institutes of Health Research Day, Bethesda, Maryland, September, 1989.
- Berko, R., Seissman, K., Colvin M., Bocian, R.C., Shlomo Ben-Efrain, and Dray, S.: Tumoricidal and Immuno-modulatory activities of drugs and implications for therapy of mice bearing a late-stage MOPC-315 Plasmacytoma. International Journal of Immuno¬ Pharmacology, Vol. 10, No. 7, pp 825-834, 1988.
- Berko, R.M., Colvin, M., Mokyr, M.B. and Dray, S.: Comparison of several drugs for their tumoricidal and immuno-modulatory activities in mice bearing a large MOPC-315 plasmacytoma. Presented at American Association for Cancer Research Meeting, Los Angeles, CA, May,1986.
- Berko, R.M. and Dubin, A.: Identification of a specific prostaglandin-binding component in rat ileum. Clinical Phys. and Biochem. Vol. 3, 307-313, 1985.
- Pearlman, W.H., Berko, R.M., Peng, L.H. and Pearlman, M.R.J.: Glucocorticoids and Lactation: In-vitro metabolism of glucocorticoids by rat mammary glands. Endocrinologia Experimentalis, Vol. 17, 175-181, 1983.
- Berko, R. M., Asare, B. and Dubin, A.: Presence of a specific prostaglandin-binding protein in rat ileum. Digestive Diseases Week, Washington, D. C., May 23-25, 1983, Abstract No. 118.
- Berko„ R. M., Asare, B. and Dubin, A.: Presence of a specific prostaglanding-binding protein in rat ileum. Clinical Chemistry, Vol. 29, Abstract No. 1210, 1983.
- Berko, R. M. and Pearlman, W.H.: The influence of 21-acylation of corticosterone on its binding affinity for corticosteroid-binding globulin (CBG). J. Steroid Biochem. Vol 14, pp 1035-1039, 1981. (Award-Winning Publication).
- Pearlman, W.H., Srzynia, C., Hampel, M., Peng, L.H. and Berko, R.M.: The levels of corticosterone-binding proteins in rat milk and coincidental serum, and the dissociation rates of the corticosterone-protein complexes. Endocinology, Vol. 108, pp 741-746, 1981.
- Berko, R.M. and Pearlman, W.H.: The influence of 21-acylation of glucocorticoids on their binding affinities for mammary glucocorticoid receptor and serum glucocorticoid¬binding globulin. The Endocrine Society, 63″I Annual Meeting, 1981, Cincinnati, OH, Abstract No. 918.
- Berko, R.M. and Pearlman, W.H.: The influence of 21-acylation of corticosterone and its interaction with proteins. Federation Proceedings, Vol. 39, pp 1722, 1980, Abstract No. 627.
- Chon, R.S., Berko, R.M. and Heizer, W.D.: Isolation and characterization of four peptide hydrolases from brush border of rat intestinal mucosa. Biochem. Biophys. Acta, Vol. 445, pp 694-719, 1976. (Prelude to Ph.D. Thesis, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina).

